Phenotypes for Ctnnb1 Tg(Prrx1-cre)98Mlgn MGI:4442425 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ctnnb1^tm4Wbm/Ctnnb1^tm4Wbm Tg(Prrx1-cre)98Mlgn/0
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm4Wbm mutation (1 available); any Ctnnb1 mutation (49 available)
Tg(Prrx1-cre)98Mlgn mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal forelimb morphology ( J:157917 )

abnormal hindlimb morphology ( J:157917 )

abnormal limb development ( J:157917 )

• at E14.5, ectopic muscle splitting and muscle mispatterning in both fore- and hindlimbs are observed, due to deletion of Tbx5 in muscle connective tissue cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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