Mouse Genome Informatics
tg
    Tg(Eno2-MFN2*R94Q)L51Ugfm/Tg(Eno2-MFN2*R94Q)L51Ugfm
involves: C57BL/6 * C57BL/6J * DBA/2
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• mice exhibit locomotor impairments compared with wild-type mice

nervous system
• mice exhibit a shift in the size of myelinated axons compared with wild-type mice
• axons contain more mitochondria than wild-type axons

Mouse Models of Human Disease
OMIM IDRef(s)
Charcot-Marie-Tooth Disease, Axonal, Type 2A2; CMT2A2 609260 J:158936