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Phenotypes Associated with This Genotype
Genotype
MGI:4440922
Allelic
Composition
Tg(Eno2-MFN2*R94Q)L51Ugfm/Tg(Eno2-MFN2*R94Q)L51Ugfm
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Eno2-MFN2*R94Q)L51Ugfm mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice exhibit locomotor impairments compared with wild-type mice

nervous system
• mice exhibit a shift in the size of myelinated axons compared with wild-type mice
• axons contain more mitochondria than wild-type axons

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Charcot-Marie-Tooth disease type 2A2 DOID:0110155 OMIM:609260
J:158936


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory