Mouse Genome Informatics
ht
    Col8a2Aca23/Col8a2+
C57BL/6J-Col8a2Aca23
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
vision/eye
N
• mice do not develop opacities and remain transparent at least until 15 months (J:158259)
• mice exhibit normal corneal epithelium proliferation, eye fundus, and visual acuity (J:158259)
• eye abnormalities are less severe than in homozygotes
• mice exhibit enlarged axis compared with wild-type mice
• mice exhibit reduced epithelium compared with wild-type mice
• contains globoid, keratoglobus-like protrusion

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Corneal Dystrophy, Fuchs Endothelial, 1; FECD1 136800 J:158259