Analysis Tools
mortality/aging
|
• fewer than expected mice are present at 4 to 5 weeks
• 12 of 129 mice die within months of birth due to anorectal malformation
|
|
• slightly fewer than expected mice are present at E18.5
|
nervous system
|
• in 16% of mice at E11.5 to E14.5
|
exencephaly
(
J:158264
)
|
• at 15- to 20-somite stages, 50% of mice exhibit open forebrain/midbrain and hindbrain regions unlike wild-type mice
• at E18.5, 3 of 19 mice exhibit exencephaly unlike wild-type mice
|
digestive/alimentary system
|
• 12 of 129 mice die within months of birth due to anorectal malformation
|
|
• 12 of 129 mice die within months of birth due to anorectal malformation
|
embryo
|
• in 16% of mice at E11.5 to E14.5
|
