Mouse Genome Informatics
tg
    Tg(GFAP-HTT*160Q)31Xjl/0
either: (involves: FVB/NCrl) or (involves: C3H * C57BL/6 * FVB/NCrl)
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• mice die by 27 months

behavior/neurological
• behavioral phenotypes worsen with age
• after 13 months of age

nervous system
• increases in aged mice
• mice older than 1.5 years exhibit increased GFAP staining in the brain compared with wild-type mice

growth/size
• in mice 16 months or older

Mouse Models of Human Disease
OMIM IDRef(s)
Huntington Disease; HD 143100 J:156460