Mouse Genome Informatics
ht
    Fgfr2tm2Ewj/Fgfr2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• 1 of 14 mice exhibit severe brain asymmetry unlike in wild-type mice
• 1 of 14 mice exhibit mild brain asymmetry unlike in wild-type mice
• rostrocaudal brain length in many mice is decreased compared to in wild-type mice
• in 2 of 14 mice
• in 1 of 14 mice
• cerebral height in many mice is increased compared to in wild-type mice
• mice exhibit cerebral asymmetry to varying degrees compared with wild-type mice
• arched in 3 of 14 mice

skeleton
• at P0, mice exhibit variation in the pattern and degree of coronal suture closure compared with wild-type mice
• mice exhibit unilateral or bilateral coronal suture synostosis unlike wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Apert Syndrome 101200 J:156940