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Phenotypes Associated with This Genotype
Genotype
MGI:4421780
Allelic
Composition
Smim3tm1Anjm/Smim3+
Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+
Trp53tm1Brd/Trp53tm1Brd
Genetic
Background
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd74tm1Anjm mutation (0 available); any Cd74 mutation (18 available)
Lmo2tm2(cre)Thr mutation (0 available); any Lmo2 mutation (14 available)
Smim3tm1Anjm mutation (0 available); any Smim3 mutation (12 available)
Trp53tm1Brd mutation (6 available); any Trp53 mutation (147 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
N
• absence of Trp53 expression completely rescues hematopoetic defects seen in mutant mice wild-type for Trp53

Mouse Models of Human Disease
OMIM ID Ref(s)
NOT Chromosome 5q Deletion Syndrome 153550 J:155870


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory