Mouse Genome Informatics
cn
    Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+
Smim3tm1Anjm/Smim3+

involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
hematopoietic system
• a decrease in granulocyte/macrophage colony-forming units in spleen and bone marrow
• by flow cytometry, there is a reduced number of megakaryocytic-erythroid progenitors and granulocyte-monocyte progenitors in the bone marrow
• there are a reduced numbers of circulating red blood cells
• a decrease in erythroid colony-forming units in the bone marrow
• in bone marrow and spleen

Mouse Models of Human Disease
OMIM IDRef(s)
Chromosome 5q Deletion Syndrome 153550 J:155870