Phenotypes for Ascl1 Neurog2 MGI:4420907 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ascl1^tm1And/Ascl1^tm1And Neurog2^tm1Fgu/Neurog2^tm1Fgu
Genetic Background	involves: 129 * 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ascl1^tm1And mutation (1 available); any Ascl1 mutation (28 available)
Neurog2^tm1Fgu mutation (0 available); any Neurog2 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal dorsal interneuron morphology ( J:98830 )

abnormal dorsal interneuron 2 morphology ( J:98830 )

• in E10.5 embryos a dramatic increase in dI2 interneuron number is seen

abnormal dorsal interneuron 3 morphology ( J:98830 )

• at E10.5 embryos show 70% loss of dI3

abnormal dorsal interneuron 4 morphology ( J:98830 )

• at E10.5 embryos show apparent loss of dI4 neurons

abnormal dorsal interneuron 5 morphology ( J:98830 )

• at E10.5 embryos show complete loss of dI5 neurons

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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