About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4412073
Allelic
Composition
Ascl1tm1And/Ascl1tm1And
Gsx2tm1Ssp/Gsx2tm1Ssp
Genetic
Background
involves: 129 * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ascl1tm1And mutation (1 available); any Ascl1 mutation (27 available)
Gsx2tm1Ssp mutation (0 available); any Gsx2 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mice have fewer calretinin+ interneurons than in wild-type mice
• at E18.5, more cells stream laterally towards the ventrolateral telencephalon compared to in wild-type mice
• mice have fewer calretinin+ interneurons than in wild-type mice
• severe at embryonic stages as determined by marker expression
• as determined by marker expression

craniofacial
• mice have fewer calretinin+ interneurons than in wild-type mice

respiratory system
• mice have fewer calretinin+ interneurons than in wild-type mice

taste/olfaction
• mice have fewer calretinin+ interneurons than in wild-type mice

growth/size/body
• mice have fewer calretinin+ interneurons than in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory