Phenotypes Associated with This Genotype

Genotype
MGI:4410441

• Allelic Composition: Tg(Prm1-cre)1Mrc/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:66393 )

N • despite male infertility, mice exhibit normal sperm counts, motility, and morphology and normal mating behavior

male infertility ( J:66393 )

♂

impaired fertilization ( J:66393 )

• male mice generate embryos that do not develop beyond the 4 cell stage with most arresting at the 2 cell stage due to chromosome scrambling unlike in wild-type mice