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Phenotypes Associated with This Genotype
Genotype
MGI:4398700
Allelic
Composition
Tg(GFAP-EFNA3)181Kln/0
Genetic
Background
involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• PTZ-treated mice exhibit increased seizure severity and more whole-body myocloni compared with similarly treated wild-type mice
• CA1 neurons exhibit dendritic beading and spine loss indicative of glutamate excitotoxicity unlike wild-type dendrites

behavior/neurological
• PTZ-treated mice exhibit increased seizure severity and more whole-body myocloni compared with similarly treated wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory