Phenotypes Associated with This Genotype

Genotype
MGI:4367795

• Allelic Composition: Scn9a^tm1.1Naas/Scn9a^tm1.1Naas
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal seizure response to electrical stimulation ( J:154118 )

• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic and minimal tonic hind limb extension compared with similarly treated wild-type mice

• however, mice do not exhibit spontaneous seizures

minimal clonic seizures ( J:154118 )

• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic compared with similarly treated wild-type mice

nervous system

abnormal seizure response to electrical stimulation ( J:154118 )

• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic and minimal tonic hind limb extension compared with similarly treated wild-type mice

• however, mice do not exhibit spontaneous seizures

minimal clonic seizures ( J:154118 )

• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic compared with similarly treated wild-type mice