Phenotypes Associated with This Genotype

Genotype
MGI:4366727

• Allelic Composition: Bmal1^tm1Bra/Bmal1^tm1Bra
• Genetic Background: involves: 129/Sv * C57BL/6 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Altered cell cycle progression in the secondary hair germ of hair follicles of Bmal1^tm1Bra/Bmal1^tm1Bra and Clock^m1Jt/Clock^m1Jt mice

integument

abnormal hair follicle matrix region morphology ( J:151782 )

• hair follicles of mutant mice contain a thickened keratinocyte strand between the dermal papilla and the club hair but lack the highly proliferative matrix required for downward growth of the hair follicle during anagen

abnormal hair cycle ( J:151782 )

• mice exhibit a delay in the first synchronized anagen that persists through out the hair cycle

• however, the duration of the hair cycle is normal

abnormal hair cycle anagen phase ( J:151782 )

• the first synchronized anagen is delayed compared to in wild-type mice