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Phenotypes Associated with This Genotype
Genotype
MGI:4360091
Allelic
Composition		 Notch2Gt(betageo)1Byg/Notch2+
Genetic
Background		 B6.129P2-Notch2Gt(betageo)1Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch2Gt(betageo)1Byg mutation (0 available); any Notch2 mutation (97 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased marginal zone B cell number ( J:146621 )
• the number of marginal zone B cells in the spleen is about one-quarter of that found in wild-type mice

hematopoietic system
decreased marginal zone B cell number ( J:146621 )
• the number of marginal zone B cells in the spleen is about one-quarter of that found in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory