Phenotypes Associated with This Genotype

Genotype
MGI:4360089

• Allelic Composition: Kif7^tm1Lex/Kif7^tm1Lex
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal limb bud morphology ( J:152551 )

• at E11.5, mice exhibit limb bud patterning defects

polydactyly ( J:152551 )

• in 77% of mice at E15.5 and E18.5

preaxial polydactyly ( J:152551 )

• at E15.5

nervous system

exencephaly ( J:152551 )

• in 9% of mice at E15.5 and E18.5

abnormal spinal cord morphology ( J:152551 )

• at E11.5, mice exhibit spinal cord patterning defects

vision/eye

microphthalmia ( J:152551 )

• in 77% of mice at E15.5 and E18.5

homeostasis/metabolism

edema ( J:152551 )

embryo

abnormal limb bud morphology ( J:152551 )

• at E11.5, mice exhibit limb bud patterning defects