immune system
• positive selection is almost completely blocked in these mice
|
• the proportion and number of double-positive thymocytes is greater than controls
|
• very few single-positive thymocytes are generated in the thymus
• peripheral CD4 T cell numbers are severely reduced
|
• very few single-positive thymocytes are generated in the thymus
|
hematopoietic system
• positive selection is almost completely blocked in these mice
|
• the proportion and number of double-positive thymocytes is greater than controls
|
• very few single-positive thymocytes are generated in the thymus
• peripheral CD4 T cell numbers are severely reduced
|
• very few single-positive thymocytes are generated in the thymus
|