About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3851494
Allelic
Composition		 Efnb3tm2.1Henk/Efnb3tm2.1Henk
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb3tm2.1Henk mutation (0 available); any Efnb3 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon pruning ( J:150550 )
• mossy fiber pruning is defective
• dentate granule cells cocultured with Cos-1 cells exhibit longer neurites than similarly treated wild-type cells due to defective pruning
abnormal axon morphology ( J:150550 )
• infra-pyramidal bundle (IPB) axons are longer than in wild-type mice

cellular
abnormal axon pruning ( J:150550 )
• mossy fiber pruning is defective
• dentate granule cells cocultured with Cos-1 cells exhibit longer neurites than similarly treated wild-type cells due to defective pruning

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory