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Phenotypes Associated with This Genotype
Genotype
MGI:3851412
Allelic
Composition		 Zfpm2tm2Sho/Zfpm2tm2Sho
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfpm2tm2Sho mutation (1 available); any Zfpm2 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal myocardial fiber physiology ( J:150452 )
• neonatal cardiomyocytes treated in culture with adeno-cre display significantly decreased quality and quantity of tubule formation
• inactivation of Zfpm2 in cardiomyocytes decreases proliferation of human umbilical vein endothelial cells in co-culture

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory