hematopoietic system
• much fewer Th2 cells are developed in vitro when nave CD4 T cells are cultured under Th2-polarizing conditions
• Th2 cells are produced under chronic N. brasiliensis infection
|
• much fewer Th2 cells are found in vitro
|
• total IgE levels are decreased 5- to 20- fold
|
• there are increased amounts of antigen-specific IgG2b levels when mice are immunized compared to controls
|
• there are increased amounts of antigen-specific IgM levels when mice are immunized compared to controls
|
homeostasis/metabolism
• IL-13 are absent in these mice
|
immune system
• much fewer Th2 cells are developed in vitro when nave CD4 T cells are cultured under Th2-polarizing conditions
• Th2 cells are produced under chronic N. brasiliensis infection
|
• much fewer Th2 cells are found in vitro
|
• total IgE levels are decreased 5- to 20- fold
|
• there are increased amounts of antigen-specific IgG2b levels when mice are immunized compared to controls
|
• there are increased amounts of antigen-specific IgM levels when mice are immunized compared to controls
|
• IL-13 are absent in these mice
|
• IFN-gamma secretion is 2-fold compared to controls when CD4 T cells are restimulated compared to controls
|
• IL-10 secretion is reduced 2-fold compared to controls when nave CD4 T cells are cultured under Th2-polarizing conditions
|
• IL-4 secretion is dramatically decreased compared to controls when nave CD4 T cells are cultured under Th2-polarizing conditions
• schistosome eggs, an antigen that induces Th2 cell responses, induces a 2-fold decreased IL-4 response than controls
|
• IL-5 secretion is dramatically decreased compared to controls when nave CD4 T cells are cultured under Th2-polarizing conditions
• schistosome eggs, an antigen that induces Th2 cell responses, induces a 2-fold decreased IL-5 response than controls
|