Analysis Tools
mortality/aging
 |
• hemizygous males show a high mortality rate by weaning that decreases with crossing into C57BL/6J background
• survival past weaning increases when mice are placed on a low-protein diet at 20-21 days of age
|
growth/size/body
renal/urinary system
|
|
• orotic acid urinary bladder stones occur frequently in hemizygous males
|
homeostasis/metabolism
|
|
• severely reduced activity of liver ornithine transcarbamylase
|
integument
sparse hair
(
J:5653
)
|
|
• absence or relative paucity of fur
|
wrinkled skin
(
J:5653
)
|
|
|
