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Phenotypes Associated with This Genotype
Genotype
MGI:3848948
Allelic
Composition
Lama2dy-8J/Lama2dy-8J
Genetic
Background
C57BL/6J-Lama2dy-8J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama2dy-8J mutation (0 available); any Lama2 mutation (71 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygotes usually die by 3 to 4 weeks of age

behavior/neurological
• hind limb paralysis is first noticeable by approximately 2 weeks of age

hearing/vestibular/ear
• in 2 homozygotes tested an increased ABR thresheld is found at the highest decibel intensity

muscle

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
congenital merosin-deficient muscular dystrophy 1A DOID:0110636 OMIM:607855
J:149729


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory