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Phenotypes Associated with This Genotype
Genotype
MGI:3842820
Allelic
Composition
H2b/H2g7
Tg(TcraR28,TcrbR28)KRNDim/0
Genetic
Background
involves: C57BL/6 * NOD * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2b mutation (23 available); any H2 mutation (262 available)
H2g7 mutation (21 available); any H2 mutation (262 available)
Tg(TcraR28,TcrbR28)KRNDim mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• rheumatoid arthritis occurs with disease onset transpiring between 25 and 35 days of age
• arthritis occurrence is established by joint inspection and measure of ankle thickness, and histological confirmation in several mice

skeleton
• rheumatoid arthritis occurs with disease onset transpiring between 25 and 35 days of age
• arthritis occurrence is established by joint inspection and measure of ankle thickness, and histological confirmation in several mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
rheumatoid arthritis DOID:7148 OMIM:180300
J:36815


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory