Phenotypes Associated with This Genotype

Genotype
MGI:3840691

• Allelic Composition: Kit^W-v/Kit^W-v
• Genetic Background: C57BL/6J-Kit^W-v/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:243758 )

• weights are normal at embryonic day 16 but by birth the body weight is retarded behind that of wildtype siblings and by 14 days of age there is more than a gram difference in average total body weight and this growth impairment continues to keep these homozygotes smaller than wild-type littermates in the adult

hematopoietic system

macrocytic anemia ( J:243758 )

• identified as early as embryonic day 16, the earliest timepoint assessed, and the severity is milder than in W/W homozygotes or compound heterozgyotes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
macrocytic anemia		DOID:2361		J:243758