Phenotypes Associated with This Genotype

Genotype
MGI:3839349

• Allelic Composition: pl/pl
• Genetic Background: involves: PERU-COPPOCK

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:14122 )

• Background Sensitivity: mice die by 14 days of age

prenatal lethality, complete penetrance ( J:14122 )

• Background Sensitivity: on some backgrounds this mutation dies before birth

growth/size/body

decreased body weight ( J:14122 )

• failed to maintain the same weight gain as normal siblings

• fostering did not normalize weight gain

postnatal growth retardation ( J:14122 )

muscle

abnormal muscle tone ( J:14122 )

• the hind limbs become weak

behavior/neurological

paraparesis ( J:14122 )