Phenotypes Associated with This Genotype

Genotype
MGI:3839293

• Allelic Composition: Atp8a2^wl-3J/Atp8a2^wl-3J
• Genetic Background: CBA/J-Atp8a2^wl-3J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality at weaning, incomplete penetrance ( J:29158 )

• most homozygotes die near wean age

nervous system

demyelination ( J:29158 )

• in the central nervous system

behavior/neurological

ataxia ( J:29158 )

• tremor in the gait and eventual diminished use of hind feet in walking

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cerebellar ataxia, mental retardation and dysequlibrium syndrome		DOID:0050997	OMIM:224050 OMIM:610185 OMIM:613227 OMIM:615268	J:222308