Phenotypes Associated with This Genotype

Genotype
MGI:3838648

• Allelic Composition: Eri1^tm1.2Anse/Eri1^tm1.2Anse
• Genetic Background: involves: BALB/cJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:146701 )

• although born in Mendelian ratios, less than 10% of mice survive to weaning with most mice dieing within the first 2 days after birth

• Background Sensitivity: just under 10% of mice survive to weaning unlike on an outbred background where more than 10% survive to weaning

growth/size/body

decreased body size ( J:146701 )

• throughout adulthood

decreased fetal size ( J:146701 )

• at E15.5

cellular

decreased cell proliferation ( J:146701 )

• mouse embryonic fibroblasts grow slower than wild-type cells after 6 to 9 passages