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Phenotypes Associated with This Genotype
Genotype
MGI:3836163
Allelic
Composition
Prph2tm1Nmc/Prph2tm1Nmc
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prph2tm1Nmc mutation (0 available); any Prph2 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• at 5 weeks, mice exhibit an increase in apoptosis in the outer nuclear layer unlike in wild-type mice
• at 5 weeks, the outer nuclear layer is only 3 or 4 nuclei thick unlike in wild-type mice
• mice exhibit 4 or 5 rows of photoreceptor nuclei at 1 months and 1 row at 4 months
• absent at 1 month of age

nervous system

cellular
• at 5 weeks, mice exhibit an increase in apoptosis in the outer nuclear layer unlike in wild-type mice

Mouse Models of Human Disease
OMIM ID Ref(s)
Retinitis Pigmentosa 7; RP7 608133 J:76490


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory