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Phenotypes Associated with This Genotype
Genotype
MGI:3834850
Allelic
Composition
Cptm1Yos/Cptm1Yos
Genetic
Background
C.129P2-Cptm1Yos
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cptm1Yos mutation (0 available); any Cp mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice treated for 4 weeks with 10mg/kg-day of rotenone starting at 13 weeks
• elevated levels of the lipid peroxidation product acrolein in hippocampal neuron cytoplasm
• ubiquitin levels elevated as well

behavior/neurological
• mice treated for 4 weeks with 10mg/kg-day of rotenone starting at 13 weeks
• reduced activity
• mice treated for 4 weeks with 10mg/kg-day of rotenone starting at 13 weeks
• tendency to stagger

Mouse Models of Human Disease
OMIM ID Ref(s)
Aceruloplasminemia 604290 J:142713


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory