Mouse Genome Informatics
tg
    Tg(SFTPC-EML4/ALK)502-4Hima/0
involves: C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• mice develop lung adenocarcinoma a few weeks after birth
• however, treatment with an ALK inhibitor reduces tumor burden

Mouse Models of Human Disease
OMIM IDRef(s)
Lung Cancer 211980 J:142679