Mouse Genome Informatics
cx
    Tg(Scgb1a1-rtTA)1Jaw/0
Tg(tetO-PIK3CA*H1047R)13Lca/0

involves: 129 * C57BL/6 * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• at 12 weeks following doxycycline treatment, mice develop lung adenocarcinomas
• however, withdrawal of doxycycline or treatment with NVP-BEZ235 leads to tumor regression

Mouse Models of Human Disease
OMIM IDRef(s)
Lung Cancer 211980 J:142254