Phenotypes for Stx1b Unc13a MGI:3832397 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Stx1b^tm1.1Sud/Stx1b^tm1.1Sud Unc13a^tm1Bros/Unc13a^tm1Bros
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stx1b^tm1.1Sud mutation (1 available); any Stx1b mutation (21 available)
Unc13a^tm1Bros mutation (1 available); any Unc13a mutation (74 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:138035 )

• homozygosity of the Stx1b mutant allele in combination with Unc13a-deficiency does not rescue the lethality observed for Unc13a-null mutants; no double homozygous mice are found at P3

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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