neoplasm
• mice develop tumors with a short median latency period of 298 days
• tumors exhibit expansive growth pattern, a high nuclear grade, and a high mitotic index
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• in 55% of mice
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• mice develop skin carcinomas
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integument
• in 55% of mice
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• mice develop skin carcinomas
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endocrine/exocrine glands
• in 55% of mice
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