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Phenotypes Associated with This Genotype
Genotype
MGI:3831161
Allelic
Composition
Foxa1tm1Khk/Foxa1tm1Khk
Foxa2tm1Khk/Foxa2+
Tg(Pdx1-cre)6Cvw/0
Genetic
Background
involves: 129 * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxa1tm1Khk mutation (0 available); any Foxa1 mutation (20 available)
Foxa2tm1Khk mutation (1 available); any Foxa2 mutation (26 available)
Tg(Pdx1-cre)6Cvw mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• unlike in mice lacking both alleles of Fox2a, pancreatic development is normal

homeostasis/metabolism
N
• mice are euglycemic


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory