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Phenotypes Associated with This Genotype
Genotype
MGI:3830726
Allelic
Composition
Etv2Gt(141.1H7)Cmhd/Etv2Gt(141.1H7)Cmhd
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv2Gt(141.1H7)Cmhd mutation (0 available); any Etv2 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Absence of an endocardial/endothelial lineage in Etv2Gt(141.1H7)Cmhd/Etv2Gt(141.1H7)Cmhd heart and embryo

mortality/aging

cardiovascular system
• at E8.5, mice lack vasculature such as the primary heart vein and the dorsal aorta
• at E8.5, mice lack endocardial/endothelial lineages in the heart and embryo
• however, this absence cannot be accounted for by increased apoptosis or decreased cell proliferation
• at E9.5 and E10.5

embryo
• between E9 and E10.5
• at E8.5, mice lack endocardial/endothelial lineages in the heart and embryo
• however, this absence cannot be accounted for by increased apoptosis or decreased cell proliferation

growth/size/body
• between E9 and E10.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory