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Phenotypes Associated with This Genotype
Genotype
MGI:3829382
Allelic
Composition
Lbric-J/Lbric-J
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lbric-J mutation (1 available); any Lbr mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• by 9 days of age

immune system
• Pelger-Huet anomaly by 9 days of age
• chromatin clumping in spleen cells seen by electron microscopy

skeleton
• tibial growth plates are markedly disorganized
• immature trabecular bone with residual cartilage

limbs/digits/tail

hematopoietic system
• Pelger-Huet anomaly by 9 days of age
• chromatin clumping in spleen cells seen by electron microscopy

integument
• by 9 days of age
• ichthyosis by 9 days of age
• ichthyosis by 9 days of age

cellular
• Pelger-Huet anomaly by 9 days of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
ichthyosis vulgaris DOID:1702 OMIM:146700
J:143838
Pelger-Huet anomaly DOID:9631 OMIM:169400
J:143838


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory