Mouse Genome Informatics
hm
    Lbric-J/Lbric-J
involves: 129S4/SvJae * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
growth/size
• by 9 days of age

immune system
• Pelger-Huet anomaly by 9 days of age
• chromatin clumping in spleen cells seen by electron microscopy

skeleton
• tibial growth plates are markedly disorganized
• immature trabecular bone with residual cartilage

limbs/digits/tail

hematopoietic system
• Pelger-Huet anomaly by 9 days of age
• chromatin clumping in spleen cells seen by electron microscopy

integument
• by 9 days of age
• ichthyosis by 9 days of age
• ichthyosis by 9 days of age

cellular
• Pelger-Huet anomaly by 9 days of age

Mouse Models of Human Disease
OMIM IDRef(s)
Ichthyosis Vulgaris 146700 J:143838
Pelger-Huet Anomaly; PHA 169400 J:143838