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Phenotypes Associated with This Genotype
Genotype
MGI:3822319
Allelic
Composition
Tg(S100b-v-erbB)4496Waw/0
Genetic
Background
involves: C57BL/6J * DBA/2J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(S100b-v-erbB)4496Waw mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mice develop oligodendroglioma
• within 6 months, 50% of mice die or are euthanized due to glioma development
• after 1 year, 24 of 38 mice die due to glioma development with the exception of 4 mice that die of unknown causes

mortality/aging
• within 6 months, 50% of mice die or are euthanized due to glioma development
• after 1 year, 24 of 38 mice (63%) die due to glioma development with the exception of 4 mice that die of unknown causes

neoplasm
• mice develop oligodendroglioma
• within 6 months, 50% of mice die or are euthanized due to glioma development
• after 1 year, 24 of 38 mice die due to glioma development with the exception of 4 mice that die of unknown causes

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
oligodendroglioma DOID:3181 J:82649


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory