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Phenotypes Associated with This Genotype
Genotype
MGI:3821875
Allelic
Composition		 Ncor1tm1Anh/Ncor1tm1Anh
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncor1tm1Anh mutation (1 available); any Ncor1 mutation (394 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating thyroxine level ( J:142045 )
• male mice exhibit a slight decrease in plasma T4 levels compared to in Ncor1tm1Anh control mice
decreased circulating LDL cholesterol level ( J:142045 )
• PTU treated mice exhibit decreased serum LDL cholesterol levels compared to in similarly treated Ncor1tm1Anh control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory