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Phenotypes Associated with This Genotype
Genotype
MGI:3821723
Allelic
Composition
Tnnt2tm1Mmto/Tnnt2+
Genetic
Background
involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnnt2tm1Mmto mutation (1 available); any Tnnt2 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• despite most causative mutations in TNNT2 resulting in cardiomyopathy in humans being dominant, heterozygous mice are viable with normal heart structure and function

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT dilated cardiomyopathy 1D DOID:0110426 OMIM:601494
J:141967


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory