Mouse Genome Informatics
hm
    Baz1bMommeD10/Baz1bMommeD10
involves: FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• most homozygotes die after birth, in the first week of life
• rare survivors at weaning

growth/size
• at weaning
• noticable in utero at E18.5

craniofacial
• shortened 12% relative to controls
• mandibular hypoplasia, particularly posteriorly
• mandibular hypoplasia
• shortened 12% relative to controls
• flattened
• upward curvature of the nasal tip
• widened bulbous forehead

skeleton
• shortened 12% relative to controls
• mandibular hypoplasia, particularly posteriorly
• mandibular hypoplasia
• shortened 12% relative to controls
• flattened

Mouse Models of Human Disease
OMIM IDRef(s)
Williams-Beuren Syndrome; WBS 194050 J:142335