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Phenotypes Associated with This Genotype
Genotype
MGI:3815321
Allelic
Composition
Nr1d1tm1Schb/Nr1d1tm1Schb
Genetic
Background
involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr1d1tm1Schb mutation (1 available); any Nr1d1 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• under both constant darkness (DD) and constant light (LL) conditions, the average period length is significantly shorter in mutants
• the distribution of period lengths is more scattered in mutants than wild-type
• light pulses delivered at CT 22 provoke dramatic phase advances in mutants compared to wild-type
• large phase advances are seen only in mutants kept in DD for longer than seven days
• the difference in phase-shifting is limited to the second half of the night

reproductive system
• litter size of homozygous females is only about half that seen in wild-type females


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory