Analysis Tools
cardiovascular system
 N |
• no abnormalities in cardiac development or heart structure are detected
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• a decrease in left ventricle fractional shortening and increase in left ventricular diameter at systole are seen in mice at 6 months of age but not in mice at 3 months of age
• decrease in function is more severe in 6 month old males compared to age matched females
• decrease in function is more severe at 12 months of age
• infusion of Apelin 13 peptides restores normal function in 6 month old mice
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• following aortic banding, mice display severe heart failure characterized by decreased fractional shortening and dilated left ventricle
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behavior/neurological
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N |
• despite data from experiments using exogenous administration of Apelin, no abnormalities in feeding behaviors or water intake are detected
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growth/size/body
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N |
• despite data from experiments using exogenous administration of Apelin, no abnormalities in weight gain are detected
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muscle
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• a decrease in left ventricle fractional shortening and increase in left ventricular diameter at systole are seen in mice at 6 months of age but not in mice at 3 months of age
• decrease in function is more severe in 6 month old males compared to age matched females
• decrease in function is more severe at 12 months of age
• infusion of Apelin 13 peptides restores normal function in 6 month old mice
|
homeostasis/metabolism
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• following aortic banding, mice display severe heart failure characterized by decreased fractional shortening and dilated left ventricle
|
