Phenotypes Associated with This Genotype

Genotype
MGI:3812187

• Allelic Composition: Ooep^{Gt(139A2)Cmhd}/Ooep^{Gt(139A2)Cmhd}
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal microtubule cytoskeleton morphology ( J:276268 )

• zygotes lack a fine meshwork of cytoplasmic F-actin resulting in acentric spindle position

maternal effect ( J:140105 )

reproductive system

reproductive system phenotype ( J:140105 )

N • despite failure to produce offspring, females release a normal number of eggs when super-ovulated and eggs can be fertilized

female infertility ( J:140105 )

♀

embryo

abnormal embryo development ( J:140105 )

• fewer than 2% of embryos from homozygous females progress beyond the 2 cell stage