Mouse Genome Informatics
hm
    Slc35d1tm1Hko/Slc35d1tm1Hko
involves: 129S1/Sv * 129X1/SvJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging

skeleton
• at birth, mice exhibit hypoplasia of the craniofacial bones
• at E15.5, the proliferating zone is greatly reduced compared to in wild-type mice and the cartilage within it is disorganized
• however, proliferation and apoptosis rates as well as chondrocyte differentiation within the zone are normal
• longitudinally short
• flattened

growth/size/body

limbs/digits/tail
• extremely short limbs

craniofacial
• at birth, mice exhibit hypoplasia of the craniofacial bones

digestive/alimentary system

Mouse Models of Human Disease
OMIM IDRef(s)
Schneckenbecken Dysplasia 269250 J:130304