Phenotypes Associated with This Genotype

Genotype
MGI:3809893

• Allelic Composition: Dlx1^tm1Jlr/Dlx1^tm1Jlr; Dlx6^tm1Jlr/Dlx6^tm1Jlr
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal cranium morphology ( J:139700 )

• the ventrolateral side of the skull exhibits a duplicate lamina obturans beside the endogenous one

abnormal pterygoid bone morphology ( J:139700 )

• unlike in wild-type mice, dentaries are shortened, fragmented and bifurcated to become bones resembling the maxilla, jugal and pterygoid

abnormal hyoid bone morphology ( J:139700 )

• mice exhibit an abnormal basihyoid and lesser horn of the hyoid

abnormal hyoid bone body morphology ( J:139700 )

abnormal hyoid bone lesser horn morphology ( J:139700 )

abnormal mandible morphology ( J:139700 )

• unlike in wild-type mice, dentaries are shortened, fragmented and bifurcated to become bones resembling the maxilla, jugal and pterygoid

abnormal zygomatic bone morphology ( J:139700 )

• unlike in wild-type mice, dentaries are shortened, fragmented and bifurcated to become bones resembling the maxilla, jugal and pterygoid

hearing/vestibular/ear

absent tympanic ring ( J:139700 )

• the ectotympanic is reduced or lost

decreased tympanic ring size ( J:139700 )

• the ectotympanic is reduced or lost

skeleton

abnormal cranium morphology ( J:139700 )

• the ventrolateral side of the skull exhibits a duplicate lamina obturans beside the endogenous one

abnormal pterygoid bone morphology ( J:139700 )

• unlike in wild-type mice, dentaries are shortened, fragmented and bifurcated to become bones resembling the maxilla, jugal and pterygoid

abnormal hyoid bone morphology ( J:139700 )

• mice exhibit an abnormal basihyoid and lesser horn of the hyoid

abnormal hyoid bone body morphology ( J:139700 )

abnormal hyoid bone lesser horn morphology ( J:139700 )

abnormal mandible morphology ( J:139700 )

• unlike in wild-type mice, dentaries are shortened, fragmented and bifurcated to become bones resembling the maxilla, jugal and pterygoid

abnormal zygomatic bone morphology ( J:139700 )

• unlike in wild-type mice, dentaries are shortened, fragmented and bifurcated to become bones resembling the maxilla, jugal and pterygoid