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Phenotypes Associated with This Genotype
Genotype
MGI:3809305
Allelic
Composition		 Dicer1tm1Snj/Dicer1tm1Snj
Tg(CAG-cre/Esr1*)5Amc/0
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1tm1Snj mutation (0 available); any Dicer1 mutation (94 available)
Tg(CAG-cre/Esr1*)5Amc mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal limb development ( J:139257 )
• at E14 to E16, tamoxifen treated mice exhibit increased cellular senescence in developing limbs compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory