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Phenotypes Associated with This Genotype
Genotype
MGI:3809288
Allelic
Composition
Nphp3pcy/Nphp3tm1Cbe
Genetic
Background
involves: C57BL/6 * CD-1 * KK/Upj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nphp3pcy mutation (0 available); any Nphp3 mutation (43 available)
Nphp3tm1Cbe mutation (0 available); any Nphp3 mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• epithelial cells have longer monocilia in dilated kidney tubules
• seen as early as 4 weeks after birth
• progressive increase in cyst size and number with age
• present in all mice

cellular
• epithelial cells have longer monocilia in dilated kidney tubules

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
nephronophthisis 3 DOID:0111114 OMIM:604387
J:139258


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory