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Phenotypes Associated with This Genotype
Genotype
MGI:3808715
Allelic
Composition		 Mesp1tm2(cre)Ysa/Mesp1+
Pofut1tm1Ysa/Pofut1tm1Ysa
Tg(CAG-cat,-Notch1)1Ysa/0
Genetic
Background		 involves: C3H * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesp1tm2(cre)Ysa mutation (1 available); any Mesp1 mutation (17 available)
Pofut1tm1Ysa mutation (0 available); any Pofut1 mutation (22 available)
Tg(CAG-cat,-Notch1)1Ysa mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart development ( J:139209 )
• trabecular layer defects observed in Pofut1tm1Ysa/Pofut1tm1Ysa Mesp1tm2(cre)Ysa/Mesp1+ mice are partially rescued

growth/size/body
enlarged heart ( J:139209 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory