Phenotypes for Ptf1a MGI:3808167 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ptf1a^tm1Pkwe/Ptf1a^tm1Pkwe
Genetic Background	involves: 129P2/OlaHsd

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptf1a^tm1Pkwe mutation (0 available); any Ptf1a mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

absent pancreas ( J:120017 )

nervous system

abnormal cerebellum development ( J:120017 )

• at E16.5, cerebellar primordium is reduced compared to in wild-type mice

absent cerebellum ( J:120017 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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