Phenotypes Associated with This Genotype

Genotype
MGI:3808021

• Allelic Composition: Tbx4^tm1.1Kng/Tbx4⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

brachydactyly ( J:139169 )

• anterior hindlimb digits are more severely reduced than posterior hindlimb digits compared to in wild-type mice with distal elements more reduced than proximal ones

short femur ( J:139169 )

• mice exhibit short femurs compared to wild-type mice but not as short as in homozygotes

short tibia ( J:139169 )

• mice exhibit short tibias compared to wild-type mice but not as short as in homozygotes

abnormal patella morphology ( J:139169 )

• patellas are shorter than in wild-type mice but not as short as in homozygotes

skeleton

short femur ( J:139169 )

• mice exhibit short femurs compared to wild-type mice but not as short as in homozygotes

short tibia ( J:139169 )

• mice exhibit short tibias compared to wild-type mice but not as short as in homozygotes

abnormal patella morphology ( J:139169 )

• patellas are shorter than in wild-type mice but not as short as in homozygotes

abnormal pelvic girdle bone morphology ( J:139169 )

• pelvic width is reduced compared to in wild-type mice but not as severely as in homozygotes